Group Members


Elizabeth Dong

Former Graduate Student

B.S. Math and Biology, Seattle Pacific University
elizabeth.n.dong [ at ]

Research Interests:

  • Research Projects
  • Publications
Dong, E.;Smith, J., Heinze, S., Alexander, N., Meiler, J.
BCL::Align-Sequence alignment and fold recognition with a custom scoring function online (2008) Gene

Karen Gregory;Elizabeth Dong, Jens Meiler, Jeffrey Conn
Allosteric modulation of metabotropic glutamate receptors: Structural insights and therapeutic potential (2011) Neuropharmacology

Philipp Schmidt;Lars Ritscher, Elizabeth N. Dong, Thomas Hermsdorf, Maxi Cöster, Doreen Wittkopf, Jens Meiler and Torsten Schoeneberg
Identification of Determinants Required for Agonistic and Inverse Agonistic Ligand Properties at the ADP Receptor P2Y12 (2012) Mol Pharmacol

Karen J. Gregory;Elizabeth D. Nguyen, Sean D. Reiff, Emma F. Squire, Shaun R. Stauffer, Craig W. Lindsley, Jens Meiler and P. Jeffrey Conn
Probing the Metabotropic Glutamate Receptor 5 (mGlu5) Positive Allosteric Modulator (PAM) Binding Pocket: Discovery of Point Mutations that Engender a “Molecular Switch” in PAM Pharmacology (2013) Molecular Pharmacology

Steven A Combs;Samuel L DeLuca, Stephanie H DeLuca, Gordon H Lemmon, David P Nannemann, Elizabeth D Nguyen, Jordan R Willis, Jonathan H Sheehan, Jens Meiler
Small-molecule ligand docking into comparative models with Rosetta (2013) Nature Protocols

Mark Turlington;Meredith J Noetzel, Aspen Celeste Chun, Ya Zhou, Rocco D Gogliotti, Elizabeth D Nguyen, Karen J Gregory, Paige N Vinson, Jerri M Rook, Kiran K Gogi, Zixiu Xiang, Thomas M Bridges, J Scott Daniels, Carrie K Jones, Colleen M Niswender, Jens Meiler, P Jeffrey Conn, Craig W Lindsley, Shaun R Stauffer
Exploration of Allosteric Agonism Structure-Activity Relationships within an Acetylene Series of Metabotropic Glutamate Receptor 5 (mGlu5) Positive Allosteric Modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254) (2013) J. Med. Chem.

Karen Joan Gregory;Elizabeth D Nguyen, Chrysa Malosh, Jeffrey L Mendenhall, Jessica Z Zic, Brittney S Bates, Meredith J Noetzel, Emma F Squire, Eric M Turner, Jerri M. Rook, Kyle A Emmitte, Shaun R. Stauffer, Craig W Lindsley, Jens Meiler, and P. Jeffrey Conn
Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site (2014) ACS Chemical Neuroscience

Christian Lis;Stefan Rubner, Martin Roatsch, Angela Berg, Tyler Gilcrest, Darwin Fu, Elizabeth Nguyen, Anne-Marie Schmidt, Harald Krautscheid, Jens Meiler & Thorsten Berg
Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells (2017) ?Scientific Reports